Scientific Publications
related to or citing UPSURGEON
Scientific Publications
related to or citing UPSURGEON
Scientific Publications
related to or citing UPSURGEON
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Temporal lobectomy for glioma surgery: how I do it
Francesco Guerrini, Michele Picciocchi, Federico Nicolosi, Giannantonio Spena
Acta Neurochir (2026). doi.org/10.1007/s00701-026-07030-y
The temporal lobe subserves language, memory, social cognition and visual processing. In the dominant hemisphere, language sites are concentrated within the posterior superior temporal gyrus and the middle-to-posterior middle and inferior temporal gyri, whereas the anterior temporal pole has a lower functional burden. Consequently, cortical mapping is recommended whenever resection extends …
Reconstructed Three-Dimensional vs. Two-Dimensional Visualization in Unilateral Biportal Endoscopic Spine Surgery: A Randomized Crossover Simulation Feasibility Study
Felix Corr, Silvio A. Heinig, Simon Behringer, Felix C. Stengel, Lorenzo Bertulli, Nader Hejrati, Oliver Bozinov, Martin N. Stienen, Stefan Motov
NeuroSci 2026, 7(5), 97; doi: 10.3390/neurosci7050097
Reconstructed three-dimensional (3D) endoscopic visualization is believed to improve depth perception and surgical performance compared with conventional two-dimensional (2D) systems. However, evidence supporting its use in unilateral biportal endoscopic (UBE) spine surgery remains limited. The objective was to compare procedural performance, task completion times, and subjective …
Iterative Virtual and Physical Simulation for Staged Separation of Total Vertical Craniopagus: The Avatar Patient Approach to Conjoined Twins
Carlo G. Giussani, Fabio Mazzoleni, Andrea Marchesi, Paolo Remida, Robert M. Lober, Akil Patel, Andrea Trezza, Mattia Moretti, Leonardo Brambilla, Giovanni Palumbo, Domenico Scopelliti, Giuseppe Citerio, Alessandra Moretto, Aida Andreassi, Erika Kacerik, Cosimo Iacca, Federico Nicolosi, Giorgio G. Carrabba, Christopher Gordon
Operative Neurosurgery, doi: 10.1227/ons.0000000000002116. June 23, 2026
Total vertical craniopagus represent one of the most complex craniofacial malformations and a demanding surgical challenge. Traditional imaging remains static and insufficient to fully anticipate dynamic venous redistribution during staged separation. We implemented an integrated virtual and physical simulation framework in the multistep separation of total vertical craniopagus twins…
Evaluation of a 3D Simulation Model for Unilateral Biportal Endoscopic Lumbar Discectomy: A Validity Study in Residency Training
Oğuz Kağan Demirtaş, Hayri Kertmen, Habibullah Dolgun, İlker Solmaz, Mehmet İlker Özer, Bilal Abbasoğlu, Süleyman Çağrı Akpınar, Baran Can Alpergin, Caner Ünlüer, Çağrı Elbir, Göktuğ Ülkü
World Neurosurgery, Vol 208, doi: 10.1016/j.wneu.2026.124887. April 2026
Unilateral biportal endoscopic (UBE) surgery is a minimally invasive technique increasingly used for lumbar spine pathologies. However, its learning curve is steep, and structured training is required before clinical practice. The aim of this study was to evaluate the educational validity and reliability of a three-dimensional simulation model for UBE lumbar discectomy according to Messick’s…
Simulating Endoscopic Transsphenoidal Surgery in a 3D Model and the Cadaver: A Preliminary Comparative Study
Cesare Zoia, Pier Paolo Mattogno, Luca Perna, Fabio Pagella, Giannantonio Spena, Federico Nicolosi, Francesco Doglietto, Mario Rigante
World Neurosurgery, Vol 206, doi: 10.1016/j.wneu.2025.124759. February 2026
The new UpSurgeOn TNSBox can contribute to a hybrid training model that combines simulation with cadaveric dissection, enhancing the acquisition of basic endoscopic surgical skills.
Neurosurgical Resident Skill Development using a Novel Simulator-Based Anterior Cervical Discectomy and Fusion Curriculum
Faith C. Robertson MD MSc MBA, Corinna C. Zygourakis MD, Janet Y. Wu BA, BM, Karen E. Malacon BA, C Coumans Jean-Valery MD, Ganesh M. Shankar MD PhD, Christopher J. Stapleton MD, Giannantonio Spena MD, Carlo Giussani MD, Brian V. Nahed MD MSc, Federico Nicolosi MD, Grazia Menna MD
World Neurosurgery (2025), doi: 10.1016/j.wneu.2025.124257. Epub 2025 Jul 4
Simulation-based training is increasingly integrated into surgical education as a method to enhance technical skills in a safe and reproducible environment. This dual-institution pilot study – conducted within the neurosurgery residency programs at Massachusetts General Hospital (MGH) and Stanford University (SU) – evaluates the feasibility and impact of integrating a 3-D printed anterior …
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Temporal lobectomy for glioma surgery: how I do it
Francesco Guerrini, Michele Picciocchi, Federico Nicolosi, Giannantonio Spena
Acta Neurochir (2026). doi.org/10.1007/s00701-026-07030-y
The temporal lobe subserves language, memory, social cognition and visual processing. In the dominant hemisphere, language sites are concentrated within the posterior superior temporal gyrus and the middle-to-posterior middle and inferior temporal gyri, whereas the anterior temporal pole has a lower functional burden. Consequently, cortical mapping is recommended whenever resection extends …
Reconstructed Three-Dimensional vs. Two-Dimensional Visualization in Unilateral Biportal Endoscopic Spine Surgery: A Randomized Crossover Simulation Feasibility Study
Felix Corr, Silvio A. Heinig, Simon Behringer, Felix C. Stengel, Lorenzo Bertulli, Nader Hejrati, Oliver Bozinov, Martin N. Stienen, Stefan Motov
NeuroSci 2026, 7(5), 97; doi: 10.3390/neurosci7050097
Reconstructed three-dimensional (3D) endoscopic visualization is believed to improve depth perception and surgical performance compared with conventional two-dimensional (2D) systems. However, evidence supporting its use in unilateral biportal endoscopic (UBE) spine surgery remains limited. The objective was to compare procedural performance, task completion times, and subjective …
Iterative Virtual and Physical Simulation for Staged Separation of Total Vertical Craniopagus: The Avatar Patient Approach to Conjoined Twins
Carlo G. Giussani, Fabio Mazzoleni, Andrea Marchesi, Paolo Remida, Robert M. Lober, Akil Patel, Andrea Trezza, Mattia Moretti, Leonardo Brambilla, Giovanni Palumbo, Domenico Scopelliti, Giuseppe Citerio, Alessandra Moretto, Aida Andreassi, Erika Kacerik, Cosimo Iacca, Federico Nicolosi, Giorgio G. Carrabba, Christopher Gordon
Operative Neurosurgery, doi: 10.1227/ons.0000000000002116. June 23, 2026
Total vertical craniopagus represent one of the most complex craniofacial malformations and a demanding surgical challenge. Traditional imaging remains static and insufficient to fully anticipate dynamic venous redistribution during staged separation. We implemented an integrated virtual and physical simulation framework in the multistep separation of total vertical craniopagus twins…
Evaluation of a 3D Simulation Model for Unilateral Biportal Endoscopic Lumbar Discectomy: A Validity Study in Residency Training
Oğuz Kağan Demirtaş, Hayri Kertmen, Habibullah Dolgun, İlker Solmaz, Mehmet İlker Özer, Bilal Abbasoğlu, Süleyman Çağrı Akpınar, Baran Can Alpergin, Caner Ünlüer, Çağrı Elbir, Göktuğ Ülkü
World Neurosurgery, Vol 208, doi: 10.1016/j.wneu.2026.124887. April 2026
Unilateral biportal endoscopic (UBE) surgery is a minimally invasive technique increasingly used for lumbar spine pathologies. However, its learning curve is steep, and structured training is required before clinical practice. The aim of this study was to evaluate the educational validity and reliability of a three-dimensional simulation model for UBE lumbar discectomy according to Messick’s…
Simulating Endoscopic Transsphenoidal Surgery in a 3D Model and the Cadaver: A Preliminary Comparative Study
Cesare Zoia, Pier Paolo Mattogno, Luca Perna, Fabio Pagella, Giannantonio Spena, Federico Nicolosi, Francesco Doglietto, Mario Rigante
World Neurosurgery, Vol 206, doi: 10.1016/j.wneu.2025.124759. February 2026
The new UpSurgeOn TNSBox can contribute to a hybrid training model that combines simulation with cadaveric dissection, enhancing the acquisition of basic endoscopic surgical skills.
Neurosurgical Resident Skill Development using a Novel Simulator-Based Anterior Cervical Discectomy and Fusion Curriculum
Faith C. Robertson MD MSc MBA, Corinna C. Zygourakis MD, Janet Y. Wu BA, BM, Karen E. Malacon BA, C Coumans Jean-Valery MD, Ganesh M. Shankar MD PhD, Christopher J. Stapleton MD, Giannantonio Spena MD, Carlo Giussani MD, Brian V. Nahed MD MSc, Federico Nicolosi MD, Grazia Menna MD
World Neurosurgery (2025), doi: 10.1016/j.wneu.2025.124257. Epub 2025 Jul 4
Simulation-based training is increasingly integrated into surgical education as a method to enhance technical skills in a safe and reproducible environment. This dual-institution pilot study – conducted within the neurosurgery residency programs at Massachusetts General Hospital (MGH) and Stanford University (SU) – evaluates the feasibility and impact of integrating a 3-D printed anterior …
Select by Categories
Select by Categories
Select by Keywords
Temporal lobectomy for glioma surgery: how I do it
Francesco Guerrini, Michele Picciocchi, Federico Nicolosi, Giannantonio Spena
Acta Neurochir (2026). doi.org/10.1007/s00701-026-07030-y
The temporal lobe subserves language, memory, social cognition and visual processing. In the dominant hemisphere, language sites are concentrated within the posterior superior temporal gyrus and the middle-to-posterior middle and inferior temporal gyri, whereas the anterior temporal pole has a lower functional burden. Consequently, cortical mapping is recommended whenever resection extends …
Reconstructed Three-Dimensional vs. Two-Dimensional Visualization in Unilateral Biportal Endoscopic Spine Surgery: A Randomized Crossover Simulation Feasibility Study
Felix Corr, Silvio A. Heinig, Simon Behringer, Felix C. Stengel, Lorenzo Bertulli, Nader Hejrati, Oliver Bozinov, Martin N. Stienen, Stefan Motov
NeuroSci 2026, 7(5), 97; doi: 10.3390/neurosci7050097
Reconstructed three-dimensional (3D) endoscopic visualization is believed to improve depth perception and surgical performance compared with conventional two-dimensional (2D) systems. However, evidence supporting its use in unilateral biportal endoscopic (UBE) spine surgery remains limited. The objective was to compare procedural performance, task completion times, and subjective …
Iterative Virtual and Physical Simulation for Staged Separation of Total Vertical Craniopagus: The Avatar Patient Approach to Conjoined Twins
Carlo G. Giussani, Fabio Mazzoleni, Andrea Marchesi, Paolo Remida, Robert M. Lober, Akil Patel, Andrea Trezza, Mattia Moretti, Leonardo Brambilla, Giovanni Palumbo, Domenico Scopelliti, Giuseppe Citerio, Alessandra Moretto, Aida Andreassi, Erika Kacerik, Cosimo Iacca, Federico Nicolosi, Giorgio G. Carrabba, Christopher Gordon
Operative Neurosurgery, doi: 10.1227/ons.0000000000002116. June 23, 2026
Total vertical craniopagus represent one of the most complex craniofacial malformations and a demanding surgical challenge. Traditional imaging remains static and insufficient to fully anticipate dynamic venous redistribution during staged separation. We implemented an integrated virtual and physical simulation framework in the multistep separation of total vertical craniopagus twins…
Evaluation of a 3D Simulation Model for Unilateral Biportal Endoscopic Lumbar Discectomy: A Validity Study in Residency Training
Oğuz Kağan Demirtaş, Hayri Kertmen, Habibullah Dolgun, İlker Solmaz, Mehmet İlker Özer, Bilal Abbasoğlu, Süleyman Çağrı Akpınar, Baran Can Alpergin, Caner Ünlüer, Çağrı Elbir, Göktuğ Ülkü
World Neurosurgery, Vol 208, doi: 10.1016/j.wneu.2026.124887. April 2026
Unilateral biportal endoscopic (UBE) surgery is a minimally invasive technique increasingly used for lumbar spine pathologies. However, its learning curve is steep, and structured training is required before clinical practice. The aim of this study was to evaluate the educational validity and reliability of a three-dimensional simulation model for UBE lumbar discectomy according to Messick’s…
Simulating Endoscopic Transsphenoidal Surgery in a 3D Model and the Cadaver: A Preliminary Comparative Study
Cesare Zoia, Pier Paolo Mattogno, Luca Perna, Fabio Pagella, Giannantonio Spena, Federico Nicolosi, Francesco Doglietto, Mario Rigante
World Neurosurgery, Vol 206, doi: 10.1016/j.wneu.2025.124759. February 2026
The new UpSurgeOn TNSBox can contribute to a hybrid training model that combines simulation with cadaveric dissection, enhancing the acquisition of basic endoscopic surgical skills.
Neurosurgical Resident Skill Development using a Novel Simulator-Based Anterior Cervical Discectomy and Fusion Curriculum
Faith C. Robertson MD MSc MBA, Corinna C. Zygourakis MD, Janet Y. Wu BA, BM, Karen E. Malacon BA, C Coumans Jean-Valery MD, Ganesh M. Shankar MD PhD, Christopher J. Stapleton MD, Giannantonio Spena MD, Carlo Giussani MD, Brian V. Nahed MD MSc, Federico Nicolosi MD, Grazia Menna MD
World Neurosurgery (2025), doi: 10.1016/j.wneu.2025.124257. Epub 2025 Jul 4
Simulation-based training is increasingly integrated into surgical education as a method to enhance technical skills in a safe and reproducible environment. This dual-institution pilot study – conducted within the neurosurgery residency programs at Massachusetts General Hospital (MGH) and Stanford University (SU) – evaluates the feasibility and impact of integrating a 3-D printed anterior …
Select by Topics
Temporal lobectomy for glioma surgery: how I do it
Francesco Guerrini, Michele Picciocchi, Federico Nicolosi, Giannantonio Spena
Acta Neurochir (2026). doi.org/10.1007/s00701-026-07030-y
The temporal lobe subserves language, memory, social cognition and visual processing. In the dominant hemisphere, language sites are concentrated within the posterior superior temporal gyrus and the middle-to-posterior middle and inferior temporal gyri, whereas the anterior temporal pole has a lower functional burden. Consequently, cortical mapping is recommended whenever resection extends …
Reconstructed Three-Dimensional vs. Two-Dimensional Visualization in Unilateral Biportal Endoscopic Spine Surgery: A Randomized Crossover Simulation Feasibility Study
Felix Corr, Silvio A. Heinig, Simon Behringer, Felix C. Stengel, Lorenzo Bertulli, Nader Hejrati, Oliver Bozinov, Martin N. Stienen, Stefan Motov
NeuroSci 2026, 7(5), 97; doi: 10.3390/neurosci7050097
Reconstructed three-dimensional (3D) endoscopic visualization is believed to improve depth perception and surgical performance compared with conventional two-dimensional (2D) systems. However, evidence supporting its use in unilateral biportal endoscopic (UBE) spine surgery remains limited. The objective was to compare procedural performance, task completion times, and subjective …
Iterative Virtual and Physical Simulation for Staged Separation of Total Vertical Craniopagus: The Avatar Patient Approach to Conjoined Twins
Carlo G. Giussani, Fabio Mazzoleni, Andrea Marchesi, Paolo Remida, Robert M. Lober, Akil Patel, Andrea Trezza, Mattia Moretti, Leonardo Brambilla, Giovanni Palumbo, Domenico Scopelliti, Giuseppe Citerio, Alessandra Moretto, Aida Andreassi, Erika Kacerik, Cosimo Iacca, Federico Nicolosi, Giorgio G. Carrabba, Christopher Gordon
Operative Neurosurgery, doi: 10.1227/ons.0000000000002116. June 23, 2026
Total vertical craniopagus represent one of the most complex craniofacial malformations and a demanding surgical challenge. Traditional imaging remains static and insufficient to fully anticipate dynamic venous redistribution during staged separation. We implemented an integrated virtual and physical simulation framework in the multistep separation of total vertical craniopagus twins…
Evaluation of a 3D Simulation Model for Unilateral Biportal Endoscopic Lumbar Discectomy: A Validity Study in Residency Training
Oğuz Kağan Demirtaş, Hayri Kertmen, Habibullah Dolgun, İlker Solmaz, Mehmet İlker Özer, Bilal Abbasoğlu, Süleyman Çağrı Akpınar, Baran Can Alpergin, Caner Ünlüer, Çağrı Elbir, Göktuğ Ülkü
World Neurosurgery, Vol 208, doi: 10.1016/j.wneu.2026.124887. April 2026
Unilateral biportal endoscopic (UBE) surgery is a minimally invasive technique increasingly used for lumbar spine pathologies. However, its learning curve is steep, and structured training is required before clinical practice. The aim of this study was to evaluate the educational validity and reliability of a three-dimensional simulation model for UBE lumbar discectomy according to Messick’s…
Simulating Endoscopic Transsphenoidal Surgery in a 3D Model and the Cadaver: A Preliminary Comparative Study
Cesare Zoia, Pier Paolo Mattogno, Luca Perna, Fabio Pagella, Giannantonio Spena, Federico Nicolosi, Francesco Doglietto, Mario Rigante
World Neurosurgery, Vol 206, doi: 10.1016/j.wneu.2025.124759. February 2026
The new UpSurgeOn TNSBox can contribute to a hybrid training model that combines simulation with cadaveric dissection, enhancing the acquisition of basic endoscopic surgical skills.
Neurosurgical Resident Skill Development using a Novel Simulator-Based Anterior Cervical Discectomy and Fusion Curriculum
Faith C. Robertson MD MSc MBA, Corinna C. Zygourakis MD, Janet Y. Wu BA, BM, Karen E. Malacon BA, C Coumans Jean-Valery MD, Ganesh M. Shankar MD PhD, Christopher J. Stapleton MD, Giannantonio Spena MD, Carlo Giussani MD, Brian V. Nahed MD MSc, Federico Nicolosi MD, Grazia Menna MD
World Neurosurgery (2025), doi: 10.1016/j.wneu.2025.124257. Epub 2025 Jul 4
Simulation-based training is increasingly integrated into surgical education as a method to enhance technical skills in a safe and reproducible environment. This dual-institution pilot study – conducted within the neurosurgery residency programs at Massachusetts General Hospital (MGH) and Stanford University (SU) – evaluates the feasibility and impact of integrating a 3-D printed anterior …