Cranial Series
Get in touch today
Cranial Series
Get in touch today
Cranial Series
Get in touch today
Cranial Series
Surgical Training Technologies for Cranial Neurosurgery
Cranial Series
Surgical Training Technologies for Cranial Neurosurgery
Life-like as
never before!
UpSurgeOn offers hyper-realistic surgical simulations featuring tissue bleeding, intricate layers, and life-like physics.
The modularity and compactness of this series enable advanced cadaver-free training in any setting, with optimized costs.


The advantages
of our simulators
Our advanced Technologies enhance skills with realistic, globally standardized simulations. Each Simulator offers 360° pre-operative solutions, blending physical and digital components for flexible, cost-effective training anytime, anywhere.
Compatible with Navigation
Upload the MRI scan on the neuronavigator and start navigating the Box.
Disposable Skulls
Perform craniotomies, dural openings, and reconstructions using the Disposable skulls. Then replace them and start again.
Augmented Reality App
Get the Neurosurgery App to explore cases, navigate 3D models, and utilize Augmented Reality on the Box to extend the procedure.
Instruments included
Non surgical instruments included to guarantee the best hands-on training experience
The advantages
of our simulators
Compatible with Navigation
Upload the MRI scan on the neuronavigator and start navigating the Box.
Disposable Skulls
Perform craniotomies, dural openings, and reconstructions using the Disposable skulls. Then replace them and start again.
Augmented Reality App
Get the Neurosurgery App to explore cases, navigate 3D models, and utilize Augmented Reality on the Box to extend the procedure.
Instruments included
Non surgical instruments included to guarantee the best hands-on training experience
The advantages
of our simulators
Compatible with Navigation
Upload the MRI scan on the neuronavigator and start navigating the Box.
Disposable Skulls
Perform craniotomies, dural openings, and reconstructions using the Disposable skulls. Then replace them and start again.
Augmented Reality App
Get the Neurosurgery App to explore cases, navigate 3D models, and utilize Augmented Reality on the Box to strategize your procedure.
Instruments included
Non surgical instruments included to guarantee the best hands-on training experience
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PterionalBox
Frontotemporal approaches to the anterior and middle cranial fossa.
Neurosurgical simulator equipped with mobile AR and navigation.
What you can explore
- II: Optic Nerve
- CA: Internal Carotid Artery
- ACA: Anterior Cerebral Artery
- A1: First segment of ACA
- AcomA: Anterior Communicating Artery
- MCA: Middle Cerebral Artery
- III: Oculomotor Nerve
- PComA:Posterior Communicating Artery
- PCA: Posterior Cerebral Artery
- Ophthalmic Artery
- Pituitary Stalk
- Perforating Arteries
- Lamina Terminalis
- Insula Heubner Artery (origin)
- Optic Chiasm
- Basilar Tip
PterionalBox
Frontotemporal approaches to the anterior and middle cranial fossa.
Neurosurgical simulator equipped with mobile AR and navigation.
Compatible with Navigation
Disposable Levels availaible
Augmented Reality App
What you can explore
- II: Optic Nerve
- CA: Internal Carotid Artery
- ACA: Anterior Cerebral Artery
- A1: First segment of ACA
- AcomA: Anterior Communicating Artery
- MCA: Middle Cerebral Artery
- III: Oculomotor Nerve
- PComA:Posterior Communicating Artery
- PCA: Posterior Cerebral Artery
- Ophthalmic Artery
- Pituitary Stalk
- Perforating Arteries
- Lamina Terminalis
- Insula Heubner Artery (origin)
- Optic Chiasm
- Basilar Tip



TemporalBox
Temporal approaches to the middle cranial fossa.
Neurosurgical simulator equipped with mobile AR and navigation.
What you can explore
- II: Optic Nerve
- ICA: Internal Carotid Artery
- ACA: Anterior Cerebral Artery
- AComA: Anterior
- Communicating Artery
- III: Oculomotor Nerve
- PComA:Posterior Communicating Artery
- PCA: Posterior Cerebral Artery
- Pituitary Stalk
- Perforating Arteries
- Optic Chiasm
- Basilar Tip
- Basal vein
- Internal Cerebral veins
- Vein of Galeno
- SCA: Superior Cerebellar Artery
- IV: Trochlear nerve
- Mesencephalus
- Tentorium
- Middle skull base fossa
- Temporal lobe
TemporalBox
Temporal approaches to the middle cranial fossa.
Neurosurgical simulator equipped with mobile AR and navigation.
Compatible with Navigation
Disposable Levels availaible
Augmented Reality App
What you can explore
- II: Optic Nerve
- ICA: Internal Carotid Artery
- ACA: Anterior Cerebral Artery
- AComA: Anterior Communicating Artery
- III: Oculomotor Nerve
- PComA:Posterior Communicating Artery
- PCA: Posterior Cerebral Artery
- Pituitary Stalk
- Perforating Arteries
- Optic Chiasm
- Basilar Tip
- Basal vein
- Internal Cerebral veins
- Vein of Galeno
- SCA: Superior Cerebellar
- Artery
- IV: Trochlear nerve
- Mesencephalus
- Tentorium
- Middle skull base fossa
- Temporal lobe



RetrosigmoidBox
Retrosigmoid approaches to the posterior cranial fossa.
Neurosurgical simulator equipped with mobile AR and navigation.
What you can explore
- III: Oculomotor Nerves
- PComA:Posterior
- Communicating Artery
- PCA: Posterior Cerebral Artery
- Pituitary Stalk
- Perforating Arteries
- Basilar artery
- Vertebral artery
- SCA: Superior Cerebellar Artery
- AICA: Anterior Inferior
Cerebellar Artery - PICA: Posterior Inferior
- Cerebellar Artery
- Mammillary bodies
- IV: Trochlear nerve
- V: Trigeminal nerve
- VI: Abducens nerve
- VII/VIII: Facial/vestibular nerves
- IX-X-XI: Mixed cranial nerves
- XII: Hypoglossal nerve
- Mesencephalus
- Pons
- Medulla oblongata
- Tentorium Posterior skull base fossa
RetrosigmoidBox
Retrosigmoid approaches to the posterior cranial fossa.
Neurosurgical simulator equipped with mobile AR and navigation.
Compatible with Navigation
Disposable Levels availaible
Augmented Reality App
What you can explore
- III: Oculomotor Nerves
- PComA:Posterior
- Communicating Artery
- PCA: Posterior Cerebral Artery
- Pituitary Stalk
- Perforating Arteries
- Basilar artery
- Vertebral artery
- SCA: Superior Cerebellar Artery
- AICA: Anterior Inferior Cerebellar Artery
- PICA: Posterior Inferior Cerebellar Artery
- Mammillary bodies
- IV: Trochlear nerve
- V: Trigeminal nerve
- VI: Abducens nerve
- VII/VIII: Facial/vestibular nerves
- IX-X-XI: Mixed cranial nerves
- XII: Hypoglossal nerve
- Mesencephalus
- Pons
- Medulla oblongata
- Tentorium Posterior skull base fossa



InterhemisphericBox
Interhemispheric approaches to the midline.
Neurosurgical simulator equipped with mobile AR and navigation.
What you can explore
- Mid frontal hemisphere
- Mid parietal hemisphere
- Third and fourth segment of the anterior cerebral artery (ACA)
- Corpus callosum
InterhemisphericBox
Interhemispheric approaches to the midline.
Neurosurgical simulator equipped with mobile AR and navigation.
Compatible with Navigation
Disposable Levels availaible
Augmented Reality App
What you can explore
- Mid frontal hemisphere
- Mid parietal hemisphere
- Third and fourth segment of the anterior cerebral artery (ACA)
- Corpus callosum



SuboccipitalBox
Suboccipital approaches to the craniocervical junction.
Neurosurgical simulator equipped with mobile AR and navigation.
What you can explore
- Basilar artery
- Vertebral artery
- SCA: Superior Cerebellar Artery
- AICA: Anterior Inferior
- Cerebellar Artery
- PICA: Posterior Inferior
- Cerebellar Artery
- Mammillary bodies
- V: Trigeminal nerve
- VII/VIII: Facial/vestibular nerves
- IX-X-XI: Mixed cranial nerves
- XII: Hypoglossal nerve
- Mesencephalus
- Pons
- Medulla oblongata
- Posterior skull base fossa
SuboccipitalBox
Suboccipital approaches to the craniocervical junction.
Neurosurgical simulator equipped with mobile AR and navigation.
Compatible with Navigation
Disposable Levels availaible
Augmented Reality App
What you can explore
- Basilar artery
- Vertebral artery
- SCA: Superior Cerebellar Artery
- AICA: Anterior Inferior
- Cerebellar Artery
- PICA: Posterior Inferior
- Cerebellar Artery
- Mammillary bodies
- V: Trigeminal nerve
- VII/VIII:
- Facial/vestibular nerves
- IX-X-XI: Mixed cranial nerves
- XII: Hypoglossal nerve
- Mesencephalus
- Pons
- Medulla oblongata
- Posterior skull base fossa



BrainTumorBox
Bleeding 5-ALA-enhanced Glioblastoma for US-guided resection.
Neurosurgical simulator equipped with mobile AR, navigation and ultrasound.
What you can explore
- Learn how to handle microsurgical instruments
- Learn how to perform perform a white matter dissection
- Learn how to perform a microsurgical resection under the microscope/exoscope
- Learn how to perform an ultrasound guided resection
- Learn how to manage intraoperative bleeding
- Resect and remove a fluorescence-guided (5-ALA) intraparenchymal glioblastoma with epicenter in the frontal white matter
BrainTumorBox
Bleeding 5-ALA-enhanced Glioblastoma for US-guided resection.
Neurosurgical simulator equipped with mobile AR, navigation and ultrasound.
Compatible with Navigation
Disposable Levels availaible
Augmented Reality App
Ultrasound
What you can explore
- Learn how to handle microsurgical instruments
- Learn how to perform perform a white matter dissection
- Learn how to perform a microsurgical resection under the microscope/exoscope
- Learn how to perform an ultrasound guided resection
- Learn how to manage intraoperative bleeding
- Resect and remove a fluorescence-guided (5-ALA) intraparenchymal glioblastoma with epicenter in the frontal white matter



AneurysmBox
Aneurysm clipping.
Neurosurgical simulator equipped with mobile AR and navigation.
What you can explore
- II: Optic Nerve
- CA: Internal Carotid Artery
- ACA: Anterior Cerebral Artery
- A1: First segment of ACA
- AcomA: Anterior Communicating Artery
- MCA: Middle Cerebral Artery
- III: Oculomotor Nerve
- PComA:Posterior Communicating Artery
- PCA: Posterior Cerebral Artery
- Ophthalmic Artery
- Pituitary Stalk Perforating Arteries
- Lamina Terminalis
- Insula Heubner Artery (origin)
- Optic Chiasm
- Basilar Tip
Aneurysm Cases
- Case 1: Middle Cerebral Artery;
- Case 2: Basilar Tip;
- Case 3: Carotid Bifurcation;
- Case 4: Anterior Communication Artery;
- Case 5: Posterior Communication Artery;
AneurysmBox
Aneurysm clipping.
Neurosurgical simulator equipped with mobile AR and navigation.
Compatible with Navigation
Disposable Levels availaible
Augmented Reality App
What you can explore
- II: Optic Nerve
- CA: Internal Carotid Artery
- ACA: Anterior Cerebral Artery
- A1: First segment of ACA
- AcomA: Anterior Communicating Artery
- MCA: Middle Cerebral Artery
- III: Oculomotor Nerve
PComA:Posterior Communicating Artery - PCA: Posterior Cerebral Artery
- Ophthalmic Artery
- Pituitary Stalk
- Perforating Arteries
- Lamina Terminalis
- Insula Heubner Artery (origin)
- Optic Chiasm
- Basilar Tip
Aneurysm Cases
- Case 1: Middle Cerebral Artery;
- Case 2: Basilar Tip;
- Case 3: Carotid Bifurcation;
- Case 4: Anterior Communication Artery;
- Case 5: Posterior Communication Artery.



FlourescentBox
5-ALA, Fluorescein and ICG fluorescence.
Neurosurgical simulator equipped with mobile AR and navigation.
What you can explore
FluorescentBox is designed to simulate 3 different fluorescences:
FLUORESCEIN, 5ALA and ICG
- Fluorescein: 1 deep frontal tumor glioma
- 5ALA: 1 superficial insular glioma
- ICG: 5 fluorescent (ICG) aneurysms in different locations (Carotid bifurcation, MCA, AComA, PComA, Basilar tip)
With the FluorescentBox you can explore all the anatomy of the PterionalBox and all 5 aneurysms of the AneurysmBox.
FlourescentBox
5-ALA, Fluorescein and ICG fluorescence.
Neurosurgical simulator equipped with mobile AR and navigation.
Compatible with Navigation
Disposable Levels availaible
Augmented Reality App
What you can explore
FluorescentBox is designed to simulate 3 different fluorescences: FLUORESCEIN, 5ALA and ICG
- Fluorescein: 1 deep frontal tumor glioma
- 5ALA: 1 superficial insular glioma
- ICG: 5 fluorescent (ICG) aneurysms in different locations (Carotid bifurcation, MCA, AComA, PComA, Basilar tip)
With the FluorescentBox you can explore all the anatomy of the PterionalBox and all 5 aneurysmsof the AneurysmBox.


TNSBox
Endoscopic Transsphenoidal approaches to a pituitary adenoma.
Neurosurgical simulator equipped with mobile AR and navigation.
What you can explore
- Septal Cartilage
- Vomer
- Mucosa
- Perpendicular plate of Ethmoid Bone
- Sphenoidal Crest
- Nasal Cavity
- Inferior Choana
- Middle Choana
- Superior Choana
- Sphenoid Sinus
- Pituitary Tumor
- Polyposis
TNSBox
Endoscopic Transsphenoidal approaches to a pituitary adenoma.
Neurosurgical simulator equipped with mobile AR and navigation.
Compatible with Navigation
Disposable Levels availaible
Instruments included
What you can explore
- Septal Cartilage
- Vomer
- Mucosa
- Perpendicular plate of Ethmoid Bone
- Sphenoidal Crest
- Nasal Cavity
- Inferior Choana
- Middle Choana
- Superior Choana
- Sphenoid Sinus
- Pituitary Tumor
- Polyposis


NavigationHead
Endoscopic Transsphenoidal approaches to a pituitary adenoma.
Neuronavigator compatible with Pterional Approaches Boxes.
What you can explore
NavigationHead
Head clamp and standard neuronavigation of PterionalBox, AneurysmBox and FluorescentBox.
Neuronavigator compatible with Pterional Approaches Boxes.
What you can explore
Neuronavigation is a technology that helps neurosurgeons design the best trajectory to an intracranial pathology. It allows you to place your scenario* inside of it, fix the head with a head holder and carry out Neuronavigation. MRI with different pathologies included (depending on the scenario) Compatible with any neuronavigation system * The pterional approaches are sold separately.
Comparison table
Features
Compare the main features of
the Cranial Series simulators

Need More Details?
Let Us Help You!
Are you feeling a bit unsure about how our Cranial simulators work? Don’t worry, we’re here to assist you!
To ensure that you have a comprehensive understanding of our simulators and their functionalities, fill out the form.
Our knowledgeable team will reach out to you with all the necessary information you need to make an informed decision.
Simply complete the form, and we’ll be in touch with you shortly.

Need More Details?
Let Us Help You!
Are you feeling a bit unsure about how our Cranial simulators work? Don’t worry, we’re here to assist you!
To ensure that you have a comprehensive understanding of our simulators and their functionalities, fill out the form.
Our knowledgeable team will reach out to you with all the necessary information you need to make an informed decision.
Simply complete the form, and we’ll be in touch with you shortly.