Cranial Series
Discover now
Cranial Series
Discover now
Cranial Series
Discover now
Cranial Series
Surgical Training Technologies for Cranial Neurosurgery
Cranial Surgical Simulation
Life-like as
never before!
UpSurgeOn offers hyper-realistic surgical simulations featuring tissue bleeding, intricate layers, and life-like physics. The modularity and compactness of this series enable advanced cadaver-free training in any setting, with optimized costs.


Discover All Cranial Offers
38% OFF
AneurysmBox
50% OFF
Aneurysm Training Kit
Out of Stock
Vascular Training Collection
41% OFF
TNSBox
47% OFF
TNS Training Kit
UpSurgeOn Cranial Technologies
Validated by Scientific Literature
Cranial Series
How it is composed


The advantages
of our Technologies
Our advanced Technologies enhance skills with realistic, globally standardized simulations. Each Simulator offers 360° pre-operative solutions, blending physical and digital components for flexible, cost-effective training anytime, anywhere.
Standard Navigation
*NavigationFrame and NavigationHead are sold separately. Check the compatibility with your navigation technology.
Mobile Navigation
Use the NavigationPen in conjunction with the Neurosurgery App for mobile neuronavigation
Disposable Skulls
Augmented Reality App
Instruments included
Standard Navigation
*NavigationFrame and NavigationHead are sold separately. Check the compatibility with your navigation technology.
Mobile Navigation
Use the NavigationPen in conjunction with the Neurosurgery App for mobile neuronavigation
Disposable Parts
Perform craniotomies, dural openings, and reconstructions using the Disposable skull, or perform other surgical procedures (such as tumor resection) with disposable cartridges.
Augmented Reality App
Instruments included
Non surgical instruments included to guarantee the best hands-on training experience.
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What you can do
Discover our hybrid training
Mental Training
Download the Neurosurgery App and learn anatomy, positioning and surgical steps of a procedure.
Mental Training
Download the Neurosurgery App and learn anatomy, positioning and surgical steps of a procedure.
Hybrid Training
Each Box comes with Augmented Reality. Open the Neurosurgery App and frame your marker to begin the experience. If available in your Box, use Mobile Navigation in the same way.
Hybrid Training
Each Box comes with Augmented Reality. Open the Neurosurgery App and frame your marker to begin the experience. If available in your Box, use Mobile Navigation in the same way.
Manual Training
Manual Training
PterionalBox
Frontotemporal approaches to the anterior and middle cranial fossa.
Neurosurgical simulator equipped with mobile AR and navigation.
Compatible with Navigation
Disposable Skulls
Augmented Reality App
What you can explore
- II: Optic Nerve
- CA: Internal Carotid Artery
- ACA: Anterior Cerebral Artery
- A1: First segment of ACA
- AcomA: Anterior Communicating Artery
- MCA: Middle Cerebral Artery
- III: Oculomotor Nerve
- PComA:Posterior Communicating Artery
- PCA: Posterior Cerebral Artery
- Ophthalmic Artery
- Pituitary Stalk
- Perforating Arteries
- Lamina Terminalis
- Insula Heubner Artery (origin)
- Optic Chiasm
- Basilar Tip



PterionalBox
Frontotemporal approaches to the anterior and middle cranial fossa.
Neurosurgical simulator equipped with mobile AR and navigation.
What you can explore
- II: Optic Nerve
- CA: Internal Carotid Artery
- ACA: Anterior Cerebral Artery
- A1: First segment of ACA
- AcomA: Anterior Communicating Artery
- MCA: Middle Cerebral Artery
- III: Oculomotor Nerve
- PComA:Posterior Communicating Artery
- PCA: Posterior Cerebral Artery
- Ophthalmic Artery
- Pituitary Stalk
- Perforating Arteries
- Lamina Terminalis
- Insula Heubner Artery (origin)
- Optic Chiasm
- Basilar Tip
TemporalBox
Temporal approaches to the middle cranial fossa.
Neurosurgical simulator equipped with mobile AR and navigation.
Compatible with Navigation
Disposable Skulls
Augmented Reality App
What you can explore
- II: Optic Nerve
- ICA: Internal Carotid Artery
- ACA: Anterior Cerebral Artery
- AComA: Anterior Communicating Artery
- III: Oculomotor Nerve
- PComA:Posterior Communicating Artery
- PCA: Posterior Cerebral Artery
- Pituitary Stalk
- Perforating Arteries
- Optic Chiasm
- Basilar Tip
- Basal vein
- Internal Cerebral veins
- Vein of Galeno
- SCA: Superior Cerebellar
- Artery
- IV: Trochlear nerve
- Mesencephalus
- Tentorium
- Middle skull base fossa
- Temporal lobe



TemporalBox
Temporal approaches to the middle cranial fossa.
Neurosurgical simulator equipped with mobile AR and navigation.
What you can explore
- II: Optic Nerve
- ICA: Internal Carotid Artery
- ACA: Anterior Cerebral Artery
- AComA: Anterior
- Communicating Artery
- III: Oculomotor Nerve
- PComA:Posterior Communicating Artery
- PCA: Posterior Cerebral Artery
- Pituitary Stalk
- Perforating Arteries
- Optic Chiasm
- Basilar Tip
- Basal vein
- Internal Cerebral veins
- Vein of Galeno
- SCA: Superior Cerebellar Artery
- IV: Trochlear nerve
- Mesencephalus
- Tentorium
- Middle skull base fossa
- Temporal lobe



RetrosigmoidBox
Retrosigmoid approaches to the posterior cranial fossa.
Neurosurgical simulator equipped with mobile AR and navigation.
What you can explore
- III: Oculomotor Nerves
- PComA:Posterior
- Communicating Artery
- PCA: Posterior Cerebral Artery
- Pituitary Stalk
- Perforating Arteries
- Basilar artery
- Vertebral artery
- SCA: Superior Cerebellar Artery
- AICA: Anterior Inferior
Cerebellar Artery - PICA: Posterior Inferior
- Cerebellar Artery
- Mammillary bodies
- IV: Trochlear nerve
- V: Trigeminal nerve
- VI: Abducens nerve
- VII/VIII: Facial/vestibular nerves
- IX-X-XI: Mixed cranial nerves
- XII: Hypoglossal nerve
- Mesencephalus
- Pons
- Medulla oblongata
- Tentorium Posterior skull base fossa
RetrosigmoidBox
Retrosigmoid approaches to the posterior cranial fossa.
Neurosurgical simulator equipped with mobile AR and navigation.
Compatible with Navigation
Disposable Skulls availaible
Augmented Reality App
What you can explore
- III: Oculomotor Nerves
- PComA:Posterior
- Communicating Artery
- PCA: Posterior Cerebral Artery
- Pituitary Stalk
- Perforating Arteries
- Basilar artery
- Vertebral artery
- SCA: Superior Cerebellar Artery
- AICA: Anterior Inferior Cerebellar Artery
- PICA: Posterior Inferior Cerebellar Artery
- Mammillary bodies
- IV: Trochlear nerve
- V: Trigeminal nerve
- VI: Abducens nerve
- VII/VIII: Facial/vestibular nerves
- IX-X-XI: Mixed cranial nerves
- XII: Hypoglossal nerve
- Mesencephalus
- Pons
- Medulla oblongata
- Tentorium Posterior skull base fossa



InterhemisphericBox
Interhemispheric approaches to the midline.
Neurosurgical simulator equipped with mobile AR and navigation.
What you can explore
- Mid frontal hemisphere
- Mid parietal hemisphere
- Third and fourth segment of the anterior cerebral artery (ACA)
- Corpus callosum
InterhemisphericBox
Interhemispheric approaches to the midline.
Neurosurgical simulator equipped with mobile AR and navigation.
Compatible with Navigation
Disposable Skulls
Augmented Reality App
What you can explore
- Mid frontal hemisphere
- Mid parietal hemisphere
- Third and fourth segment of the anterior cerebral artery (ACA)
- Corpus callosum



SuboccipitalBox
Suboccipital approaches to the craniocervical junction.
Neurosurgical simulator equipped with mobile AR and navigation.
What you can explore
- Basilar artery
- Vertebral artery
- SCA: Superior Cerebellar Artery
- AICA: Anterior Inferior
- Cerebellar Artery
- PICA: Posterior Inferior
- Cerebellar Artery
- Mammillary bodies
- V: Trigeminal nerve
- VII/VIII: Facial/vestibular nerves
- IX-X-XI: Mixed cranial nerves
- XII: Hypoglossal nerve
- Mesencephalus
- Pons
- Medulla oblongata
- Posterior skull base fossa
SuboccipitalBox
Suboccipital approaches to the craniocervical junction.
Neurosurgical simulator equipped with mobile AR and navigation.
Compatible with Navigation
Disposable Skulls
Augmented Reality App
What you can explore
- Basilar artery
- Vertebral artery
- SCA: Superior Cerebellar Artery
- AICA: Anterior Inferior
- Cerebellar Artery
- PICA: Posterior Inferior
- Cerebellar Artery
- Mammillary bodies
- V: Trigeminal nerve
- VII/VIII:
- Facial/vestibular nerves
- IX-X-XI: Mixed cranial nerves
- XII: Hypoglossal nerve
- Mesencephalus
- Pons
- Medulla oblongata
- Posterior skull base fossa



TNSBox
Endoscopic Transsphenoidal approaches to a pituitary adenoma.
Neurosurgical simulator equipped with mobile AR and navigation.
What you can explore
- Septal Cartilage
- Vomer
- Mucosa
- Perpendicular plate of Ethmoid Bone
- Sphenoidal Crest
- Nasal Cavity
- Inferior Choana
- Middle Choana
- Superior Choana
- Sphenoid Sinus
- Pituitary Tumor
- Polyposis
TNSBox
Endoscopic Transsphenoidal approaches to a pituitary adenoma.
Neurosurgical simulator equipped with mobile AR and navigation.
Augmented Reality App
Disposable Skulls
Instruments included
What you can explore
- Septal Cartilage
- Vomer
- Mucosa
- Perpendicular plate of Ethmoid Bone
- Sphenoidal Crest
- Nasal Cavity
- Inferior Choana
- Middle Choana
- Superior Choana
- Sphenoid Sinus
- Pituitary Tumor
- Polyposis



AneurysmBox
Aneurysm clipping.
Neurosurgical simulator equipped with mobile AR and navigation.
What you can explore
- II: Optic Nerve
- CA: Internal Carotid Artery
- ACA: Anterior Cerebral Artery
- A1: First segment of ACA
- AcomA: Anterior Communicating Artery
- MCA: Middle Cerebral Artery
- III: Oculomotor Nerve
- PComA:Posterior Communicating Artery
- PCA: Posterior Cerebral Artery
- Ophthalmic Artery
- Pituitary Stalk Perforating Arteries
- Lamina Terminalis
- Insula Heubner Artery (origin)
- Optic Chiasm
- Basilar Tip
Aneurysm Cases
- Case 1: Middle Cerebral Artery;
- Case 2: Basilar Tip;
- Case 3: Carotid Bifurcation;
- Case 4: Anterior Communication Artery;
- Case 5: Posterior Communication Artery;
AneurysmBox
Aneurysm clipping.
Neurosurgical simulator equipped with mobile AR and navigation.
Compatible with Navigation
Disposable Skulls
Augmented Reality App
What you can explore
- II: Optic Nerve
- CA: Internal Carotid Artery
- ACA: Anterior Cerebral Artery
- A1: First segment of ACA
- AcomA: Anterior Communicating Artery
- MCA: Middle Cerebral Artery
- III: Oculomotor Nerve
PComA:Posterior Communicating Artery - PCA: Posterior Cerebral Artery
- Ophthalmic Artery
- Pituitary Stalk
- Perforating Arteries
- Lamina Terminalis
- Insula Heubner Artery (origin)
- Optic Chiasm
- Basilar Tip
Aneurysm Cases
- Case 1: Middle Cerebral Artery;
- Case 2: Basilar Tip;
- Case 3: Carotid Bifurcation;
- Case 4: Anterior Communication Artery;
- Case 5: Posterior Communication Artery.



BrainTumorBox
Bleeding 5-ALA-enhanced Glioblastoma for US-guided resection.
Neurosurgical simulator equipped with mobile AR, navigation and ultrasound.
What you can explore
- Learn how to handle microsurgical instruments
- Learn how to perform perform a white matter dissection
- Learn how to perform a microsurgical resection under the microscope/exoscope
- Learn how to perform an ultrasound guided resection
- Learn how to manage intraoperative bleeding
- Resect and remove a fluorescence-guided (5-ALA) intraparenchymal glioblastoma with epicenter in the frontal white matter
BrainTumorBox
Bleeding 5-ALA-enhanced Glioblastoma for US-guided resection.
Neurosurgical simulator equipped with mobile AR, navigation and ultrasound.
Compatible with Navigation
Disposable Skulls
Augmented Reality App
Ultrasound
What you can explore
- Learn how to handle microsurgical instruments
- Learn how to perform perform a white matter dissection
- Learn how to perform a microsurgical resection under the microscope/exoscope
- Learn how to perform an ultrasound guided resection
- Learn how to manage intraoperative bleeding
- Resect and remove a fluorescence-guided (5-ALA) intraparenchymal glioblastoma with epicenter in the frontal white matter



FluorescentBox
5-ALA, Fluorescein and ICG fluorescence.
Neurosurgical simulator equipped with mobile AR and navigation.
What you can explore
- Fluorescein: Glioblastoma (WHO Grade IV)
- 5ALA: Anaplastic Astrocytoma (WHO Grade III)
- ICG: 5 fluorescent (ICG) aneurysms in different locations (Carotid bifurcation, MCA, AComA, PComA, Basilar tip)
ICHBox
Intracerebral Hemorrhage (ICH) Simulator for Advanced Neurosurgical Training
Neurosurgical simulator equipped with mobile AR and navigation
Compatible with Navigation
Disposable Skulls
Augmented Reality App
What you can explore
- Learn how to handle microsurgical instruments: Develop proficiency with microsurgical tools necessary for delicate neurovascular procedures.
- Learn how to perform white matter dissection: Gain expertise in dissecting white matter to access and manage intracerebral hemorrhages.
- Learn how to perform a microsurgical resection under the microscope/exoscope: Enhance your skills in resecting hemorrhagic tissue using high-precision optical instruments.
- Learn how to manage intraoperative bleeding: Master techniques to effectively control bleeding during neurosurgical interventions.


ICHBox
Intracerebral Hemorrhage (ICH) Simulator for Advanced Neurosurgical Training
Neurosurgical simulator equipped with mobile AR and navigation
What you can explore
- Learn how to handle microsurgical instruments: Develop proficiency with microsurgical tools necessary for delicate neurovascular procedures.
- Learn how to perform white matter dissection: Gain expertise in dissecting white matter to access and manage intracerebral hemorrhages.
- Learn how to perform a microsurgical resection under the microscope/exoscope: Enhance your skills in resecting hemorrhagic tissue using high-precision optical instruments.
- Learn how to manage intraoperative bleeding: Master techniques to effectively control bleeding during neurosurgical interventions.
FluorescentBox
5-ALA, Fluorescein and ICG fluorescence.
Neurosurgical simulator equipped with mobile AR and navigation.
Compatible with Navigation
Disposable Skulls
Augmented Reality App
What you can explore
FluorescentBox is designed to simulate 3 different fluorescences: FLUORESCEIN, 5ALA and ICG
- Fluorescein: Glioblastoma (WHO Grade IV)
- 5ALA: Anaplastic Astrocytoma (WHO Grade III)
- ICG: 5 fluorescent (ICG) aneurysms in different locations (Carotid bifurcation, MCA, AComA, PComA, Basilar tip)
With the FluorescentBox you can explore all the anatomy of the PterionalBox and all 5 aneurysmsof the AneurysmBox.


NavigationHead
Head clamp and standard neuronavigation of PterionalBox, AneurysmBox and FluorescentBox.
Neuronavigator compatible with Pterional Approaches Boxes.
What you can explore
NavigationHead
Head clamp and standard neuronavigation of PterionalBox, AneurysmBox and FluorescentBox.
Neuronavigator compatible with Pterional Approaches Boxes.
What you can explore
Neuronavigation is a technology that helps neurosurgeons design the best trajectory to an intracranial pathology. It allows you to place your scenario* inside of it, fix the head with a head holder and carry out Neuronavigation. MRI with different pathologies included (depending on the scenario) Compatible with any neuronavigation system * The pterional approaches are sold separately.


NavigationHead
Hemispheric Approaches
Neuronavigation Technology System compatible with Hemispheric Approaches
Choose your Scenario
- Interhemispheric Scenario: Life-like reproduction of an inter hemispheric approach with explorable anatomy;
- BrainTumor Resection: Bleeding 5-ALA-enhanced Glioblastoma for US-guided resection;
- Stereotactic Hemispheric Scenario (with a disposable brain for stereotactic procedures): A completely disposable brain for different procedures such as stereotactic navigation or brain biopsy.
- Intracerebral Hemorrhage Drainage (ICH): Disposable scenario for intracerebral hemorrhage treatment procedures
NavigationHead
Hemispheric Approaches
Neuronavigation Technology System compatible with Hemispheric Approaches
Choose Your Scenario
- Interhemispheric Scenario: Life-like reproduction of an inter hemispheric approach with explorable anatomy;
- BrainTumor Resection: Bleeding 5-ALA-enhanced Glioblastoma for US-guided resection;
- Stereotactic Hemispheric Scenario (with a disposable brain for stereotactic procedures): A completely disposable brain for different procedures such as stereotactic navigation or brain biopsy.
- Intracerebral Hemorrhage Drainage (ICH): Disposable scenario for intracerebral hemorrhage treatment procedures;
Comparison table
Features
Compare the main features of
the Cranial Series simulators


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